Arkansas continues to struggle on the road.
The Razorbacks found themselves in a tie game with Ole Miss midway through the second half but again saw a SEC road game slip away.
The Rebels closed the game on a 24-12 run as they pulled out a 76-64 win.
Ole Miss moves to a perfect 4-0 in league play while Arkansas is now 2-2 in the SEC.
Arkansas (11-6) got 16 points, four rebounds and four blocks from Marshawn Powell but the Hogs shot just 39.4 percent and committed 18 turnovers. BJ Young finished with 14 points while Hunter Mickelson added 10 points with a team high 8 rebounds.
Ole Miss (15-2) was paced by Marshall Henderson with 16 points despite shooing 5-of-16 from the field. The Rebels had five players in double figures including a pair of double-doubles. Murphy Holloway had 15 points and 11 rebounds while Reginald Buckner finished with 10 points and 10 rebounds.
Arkansas got just 15 points from its bench. Nick Williams scored 14 points by himself off the Ole Miss bench.
